陈杜刚,博士,副教授,硕士生导师
地址:湖北省武汉市东湖新技术开发区光谷一路206号,云顶集团
邮编:430205
Email:dg.chen@163.com
教育背景
2007年−2012年 武汉大学,化学与分子科学学院,博士
2003年−2007年 武汉大学,化学与分子科学学院,学士
工作履历
2018年至今 云顶集团官网,云顶集团,副教授
2019年−2020年 Georgia Institute of Technology,访问学者
2016年−2018年 云顶集团官网,云顶集团,讲师
研究领域
(1)荧光纳米材料及其生物医学应用:聚集诱导发光,化学传感,光疗试剂,生物成像
(2)高端磷/硅化学品:单分散纳/微米硅,硅气凝胶,磷系阻燃剂
招收化学工程、化学工艺、物理化学、药物化学、制药工程、材料工程等方向的研究生。
学术成果
近年来代表性SCI论文:
(1) Dai, J.; Xue, H.;Chen,D.; Lou, X.; Xia, F.; Wang, S., Aggregation-induced emission luminogens forassisted cancer surgery.Coord. Chem. Rev.2022,464,214552.
(2) Liang, W.; Nie, G.; Che, J.; Zhang, Z.;Chen,D.; Wu, W., A ratiometric hypochlorite-specific nanoprobe constructed byrationally designed AIE luminogen for fluorescence imaging of alcoholic liverdisease.Sens. Actuators B2023,384, 133648.
(3) Feng, Y.; Nie, G.; Liang, W.; Li, W.; Zhang, Y.;Wang, K.;Chen, D., Real-time imaging of acute alcoholic liver injury invivo via a robust viscosity probe with aggregation-induced emission nature.Sens.Actuators B2022,355, 131285.
(4)Chen, D.; Feng, Y., Recent Progress ofGlutathione (GSH) Specific Fluorescent Probes: Molecular Design, PhotophysicalProperty, Recognition Mechanism and Bioimaging.Crit. Rev. Anal. Chem.2022,52, 649-666.
(5)Chen, D.; Long, Z.; Zhong, C.; Chen, L.;Dang, Y.; Hu, J.-J.; Lou, X.; Xia, F., Highly Efficient Near-Infrared Photosensitizerswith Aggregation-Induced Emission Characteristics: Rational Molecular Designand Photodynamic Cancer Cell Ablation.ACS Appl. Bio Mater.2021,4, 5231-5239.
(6) Chen, L.; Li, J.;Chen, D., RecentAdvances in Fluorescent Probes for Biothiols.Chin. J. Org. Chem.2021,41, 611-623.
(7) Nie, G.; Zhang, Y.; Zhou, Z.; Xu, J.; Wang, H.;Chen,D.; Wang, K., Dynamic evaluation of the protective effect of Dendrobiumofficinale polysaccharide on acute alcoholic liver injury mice in vitro and invivo by NIR fluorescence imaging.Anal. Bioanal. Chem.2021,413,5715-5724.
(8) Xiang, Y.; Yu, X.; Li, Y.; Chen, J.; Wu, J.;Wang, L.;Chen, D.; Li, J.; Zhang, Q., Covalent organic framework as anefficient fluorescence-enhanced probe to detect aluminum ion.Dyes Pigm.2021,195, 109710.
(9) Chen, L.; Feng, Y.; Dang, Y.; Zhong, C.;Chen,D., A deep-red emission fluorescent probe with long wavelength absorptionfor viscosity detection and live cell imaging.Anal. Bioanal. Chem.2020,412, 7819-7826.
(10) Long, Z.; Chen, L.; Dang, Y.;Chen, D.;Lou, X.; Xia, F., An ultralow concentration of two-photon fluorescent probe forrapid and selective detection of lysosomal cysteine in living cells.Talanta2019,204, 762-768.
(11)Chen, D.; Long, Z.; Dang, Y.; Chen, L.,A new fluorescent probe for specific detection of cysteine with facilepreparation and living cell imaging.Dyes Pigm.2019,166,266-271.
(12)Chen, D.; Long, Z.; Dang, Y.; Chen, L.,A novel fluorescent probe with red emission and a large Stokes shift forselective imaging of endogenous cysteine in living cells.Analyst2018,143, 5779-5784.
(13)Chen, D.; Yang, J.; Dai, J.; Lou, X.;Zhong, C.; Yu, X.; Xia, F., A low background D–A–D type fluorescent probe forimaging of biothiols in living cells.J. Mater. Chem. B2018,6,5248-5255.
(14) Sun, Y.; Luo, S.; Sun, H.; Zeng, W.; Ling, C.;Chen,D.; Chan, V.; Liao, K., Engineering closed-cell structure in lightweightand flexible carbon foam composite for high-efficient electromagnetic interferenceshielding.Carbon2018,136, 299-308.
(15) Sun, Y.; Zeng, W.; Sun, H.; Luo, S.;Chen,D.; Chan, V.; Liao, K., Inorganic/polymer-graphene hybrid gel as versatileelectrochemical platform for electrochemical capacitor and biosensor.Carbon2018,132, 589-597.
授权发明专利:
(1)一种发射近红外光的荧光染料及其制备方法,ZL201910519410.X
(2)一种溶酶体靶向荧光探针及其制备方法,ZL201710470889.3
(3)一种双通道铜离子检测试纸及其制备方法,ZL201710952218.0
(4)一种远红光溶酶体荧光探针及其制备方法和应用,ZL202011175030.8
(5)具有近红外发射、高单线态氧产率的聚集诱导发光型光敏剂及其制备方法、应用,ZL202110338852.1
(6)具有聚集诱导发光特性的水溶性荧光探针及其制备方法、应用,ZL202111009124.2
科研项目
国家自然科学基金青年项目,主持
教育厅重点项目,主持
其它荣誉
指导本科生/研究生多人次获“互联网+”大学生创新创业大赛校赛奖项;指导研究生多人次获“优秀硕士学位论文”;指导本科生以第一作者发表论文。